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Position Details

Gene Expression Postdoc Position

Medicine, Biochemistry and Pharmacology

Greetings! The Blind Lab has an open postdoc position to study how 2nd messenger signaling molecules generated in chromatin alter histone acetylation and gene expression. 

We recently discovered a new gene regulatory mechanism in human glioblastoma cell lines. This new mechanism revolves around a kinase our lab studies, which generates inositide 2nd messenger signaling molecules. We discovered that this kinase is recruited to thousands of transcriptional start sites, regulating gene expression in a kinase-dependent manner and altering histone acetylation and methylation. 

The ideal candidate will need to have an interest in helping others in the lab and have some skills in mammalian cellular biochemistry, gene expression analysis, genomics and/or HDAC biology. Experience with or eagerness to learn chromatin immunoprecipitation (ChIP), transcriptome (RNA-seq), RT-qPCR, qPCR and other gene expression analyses is ideal. 

If you're doubting your fit, I encourage you to apply. I have many other projects in structural biology, genomics and drug design/screening you might be a great fit for!

Thank you!

Ray Blind

Please send an email or cover letter expressing your interest, along with an updated CV (including manuscripts in prep, etc.), to Ray Blind. I will confirm receipt of your application.

Ray Blind, PhD
Email
Phone: (615) 936-1037
2020-01-28 14:38:50

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