Postdoctoral position to investigate pancreatic islet ion channels that control hormone secretion and their therapeutic potential for treating diabetes.
|Molecular Physiology and Biophysics|
An NIH funded postdoctoral fellowship is available in the Jacobson laboratory for a highly-motivated scientist interested in diabetes research. Our focus is on the mechanisms that influence pancreatic islet calcium homeostasis and hormone secretion under physiological and diabetic conditions. The goal is to identify pathways that can be therapeutically targeted to reduce pancreatic islet dysfunction and restore euglycemia in patients with diabetes. The primary models employed in these projects include: human islets, rodent islets, pancreatic slices and cultured cells. The research utilizes cutting edge approaches in molecular biology, fluorescent microscopy (both epifluorescent and confocal), electrophysiology, biochemistry, virus expression of genetically encoded indicators for calcium and membrane potential, and transgenic mouse models.
The postdoctoral fellow will be expected to design and efficiently carry out experiments, communicate effectively and be willing to work collaboratively with other members of our team.
To apply, please send a cover letter describing past training, research interests and career goals, a detailed CV and contact information of three referees to David Jacobson.
|David Jacobson, PhD
Phone: (615) 875-7655